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Publications

Enhanced membrane stability of mRNA nanoparticle derived TNFSF14 results in superior T-cell and NK cell stimulation

April 11, 2024

American Association for Cancer Research Annual Meeting (2024)

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NTX-470, a novel multispecific T cell engager expressed from mRNA targets PSMA and STEAP1 prostate cancer antigens to generate enhanced functional activity

April 11, 2024

American Association for Cancer Research Annual Meeting (2024)

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134 mNTX-250, a novel multimodal HPV-16 mRNA-based therapeutic, induces potent anti-tumor responses and establishes HPV-16 specific immune memory

November 2, 2023

Journal for ImmunoTherapy of Cancer (2023)

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1359 NTX-0471, engineered multivalent SIRPa and bispecific SIRPa-antiCCR4 molecules demonstrate superior activity providing path for mRNA expressed in-vivo biologics

November 2, 2023

Journal for ImmunoTherapy of Cancer (2023)

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Mapping of shared tumor antigen reactivity with nanoparticle encapsulated mRNA in prostate cancer patients

April 15, 2023

American Association for Cancer Research Annual Meeting (2023)

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Modification of mRNA-encoded HPV16 antigens to include endolysosomal trafficking domains drives cross-presentation and results in superior in vivo and ex vivo antigen-specific responses

April 1, 2023

American Association for Cancer Research Annual Meeting (2023)

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Local delivery of mRNA immunotherapy encoding HPV16 antigen, IL-12, and LIGHT/TNFSF14 results in superior immunogenicity and tumor clearance in a murine model of HPV16-driven cancer

April 1, 2023

American Association for Cancer Research Annual Meeting (2023)

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NTX-250, a Multimodal mRNA-based Immunotherapy, Eradicates Large Established Tumors in a Stringent Mouse Model of HPV16-Driven Cancer

November 7, 2022

Society for Immunotherapy of Cancer Annual Meeting (2022)

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